Focus on diagnostics
We process the data

Cloud-based genetic diagnostics to accelerate laboratory workflows and enhance patient care.

One turnkey solution for all clinical NGS applications

Solution

The varvis® genomics software is a complete solution for clinical diagnostics, supporting NGS raw data processing, genomics data management, and variant interpretation. Automated CNV and SNV analysis are clinically validated and completely integrated into the NGS workflow.

varvis genomics platform - Bioinformatics pipeline

Bioinformatics

Automated. Validated. Fast.

Our automated bioinformatics pipeline processes raw next-generation sequencing data from bcl, fastq or bam files. On completion of all bioinformatics analyses, including alignment and clinically validated CNV/SNV/Indel variant calling, the results are annotated and visualized in the varvis® software automatically. Pipeline validation is provided as a service – updates are included.

varvis genomics software

varvis® genomics software

Made for use in clinical diagnostics

The varvis® software is a clinical decision support system (CDS) and allows you to review, filter, and classify genetic variants. In addition, it includes your own comprehensive variant database. It supports the clinical decision-making process and is the first genomics end-to-end software certified as IVDR Class C device.

varvis genomics platform - Annotation

Annotation

Always up to date

Our reference database, allexes®, provides the data for variant annotation to the varvis® software. The allexes® database does not only deliver the most recent versions of public databases, but also provides access to aggregated genomic reference data from all our users while continuing to be compliant with HIPAA and EU regulations.

Key benefits

 
Automated QC

Important quality metrics are monitored automatically for every single NGS sample, but also across batches over time. Don't waste a moment on manual QC.

 
Push the button

Convenient filtering options such as inheritance filters and virtual panels allow you to filter from thousands of detected SNVs and CNVs. Within seconds.

  
Supreme expert support

Our dedicated team provides first-class support regarding workflow optimization, technical issues, training and documentation – even for the tricky cases. We are here to help!

 
NGS validation as a service

Simply sequence the appropriate reference sample to validate your workflow – we take care of the rest and provide you with a validation report. Regular updates are included.

Use cases

varvis genomics platform use case - NGS panels

NGS panels

Identify rare and causative SNV and CNV in a single validated process and replace conventional PCR-based methods.

varvis genomics platform use case - whole exome sequencing

Whole exome
sequencing

Do you need more than 15 minutes to interpret a whole exome? Accelerate WES interpretation by combining phenotype, family and inheritance information.

varvis genomics platform use case - liquid biopsy

Liquid biopsy

Detect somatic variants with validated high sensitivity using state-of-the-art molecular barcoding technologies.

varvis genomics platform use case - carrier screening

Carrier screening

Even the most complex scenarios are well covered in a single carrier screening filter to solve your cases with just a few clicks.

See for yourself how the varvis® software can accelerate your laboratory workflows and increase your diagnostic yield.

Let's schedule a demo!

Testimonials

Read more

varvis® blog - Update to gnomAD v4.1: Key features

Update to gnomAD v4.1: Key features

by Dr. Roberta Trunzo, August 27, 2024

The varvis® software now includes the latest version of the Genome Aggregation Database (gnomAD), providing updated annotations for whole exome and whole genome data. This article describes the enhancements and implications of the update to the new version 4.1, particularly for clinical diagnostics.

Read more

varvis® blog - The varvis® Software: The first genomics end-to-end software certified as IVDR Class C device

The varvis® Software: The first genomics end-to-end software certified as IVDR Class C device

by Dr. Ben Liesfeld, May 31, 2024

Genetic diagnostic laboratories now have access to the first complete genomics software solution which is certified as a Class C device under IVDR. This will significantly reduce the effort required for legally compliant documentation of in-house tests.

Read more

varvis® blog - Q&A: The role of the IVDR conformity assessment in genetic diagnostics

Q&A: The role of the IVDR conformity assessment in genetic diagnostics

by Dr. Ben Liesfeld & Dr. Sonja Strunz,
May 31, 2024

Now that the regulation on in-vitro diagnostic devices (IVDR) explicitly regulates in-house devices, or laboratory-developed tests (LDTs), in the European Union, the selection of properly CE-labeled devices is increasingly important to health institutions like genetic testing laboratories.'

Read more

Find more interesting articles in our blog

Get our latest news

Limbus Medical Technologies GmbH will use the information you provide on this form to send you our newsletter and all relevant information about us. You can change your mind at any time by clicking the unsubscribe link in the footer of any newsletter you receive from us, or by contacting us via dpo@limbus-medtec.com.