Focus on diagnostics
We process the data

The varvis™ genomics platform is a complete solution for clinical diagnostics, supporting NGS raw data processing, genomics data management, and variant interpretation.

Key benefits

  Up to date

Use continuously updated public data from sources like gnomAD and ClinVar.


Access more than 6000 diligently curated WES cases including all variants and phenotype descriptions through our network.

  Overnight express

No matter how many samples or how many sequencing runs you have: our fully automated process delivers results overnight.

  80% savings

Our clinically validated CNV analysis provides significant cost savings compared to ligation based CNV detection methods.

varvis  Approved

varvis™ is a medical device Class I according to MDD 93/42/EEC.

  Deep phenotyping

varvis™ enables standardized phenotyping using ontologies like HPO to improve the accuracy of your diagnosis.



varfeed™ automates the processing of raw next-generation sequencing data from bcl, fastq or bam files. It performs alignment, SNP/Indel variant calling and a clinically validated CNV analysis. All results are handed over to varvis™ automatically.

varvis™ is a clinical decision support system (CDS) and allows you to review, filter and classify genetic variants. varvis™ is your own comprehensive variant database. It supports the clinical decision-making process and is thus a CE medical device.

allexes™ provides the data for variant annotation to varvis™. allexes™ does not only deliver the most recent versions of public databases, but also access to aggregated genomic reference data from all our users.



varvis™ is compliant with European medical device regulations as well as with HIPAA and the new EU data privacy regulation.

 Data availability

Never deal with the management of files again. Start to review large data sets with one click. We offer long-term archival options on request.

 Data protection

Confidentiality of patient data is integral part of the Varvis platform design. Data is encrypted both in transit and at rest. Data that is shared through allexes is de-identified and aggregated.


Martin Zenker

“Limbus demonstrated the clinical validity of its varfeed CNV detection algorithms. We now use the varfeed CNV analysis as a very cost-effective and sensitive first-line diagnostics.”

Prof. Martin Zenker, MD, University of Magdeburg

“The varvis platform has been designed from the start with the medical application in mind. The platform conveniently supports our diagnostic workflow. The service is excellent and the team is very reliable. The list of features is growing surprisingly fast.”

Rami Abou Jamra, MD, University of Leipzig, GND
Rami Abou Jamra

Anne Gregor

“The varvis platform allows us to process, manage, and compare thousands of WES data sets. This enables us to make new discoveries and increase the diagnostic yield.”

Anne Gregor, Ph. D., Rockefeller University, member of the GND consortium

Get in touch


Limbus Medical Technologies GmbH
Schillerplatz 1 18055 Rostock Germany

Our Team